Rosai-Dorfman disease with spontaneous resolution: case report of a child

Rosai-Dorfman disease is a self-limiting condition caused by histiocyte proliferation within the sinusoids of lymph nodes and in extranodal tissue. It is a rare disease, particularly in children, that progresses with extensive lymphadenopathy. This paper reports on the case of a 2-year-old child wit...

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Main Authors:	Lima, Felipe Barbosa, Barcelos, Pedro Samuel de Valões, Constâncio, Ana Paula Nunes, Nogueira, Cleto Dantas, Melo-Filho, Antônio Aldo
Format:	Online
Language:	English
Published:	Associação Brasileira de Hematologia e Hemoterapia 2011
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415761/

id	pubmed-3415761
recordtype	oai_dc
spelling	pubmed-34157612012-10-04 Rosai-Dorfman disease with spontaneous resolution: case report of a child Lima, Felipe Barbosa Barcelos, Pedro Samuel de Valões Constâncio, Ana Paula Nunes Nogueira, Cleto Dantas Melo-Filho, Antônio Aldo Case Report Rosai-Dorfman disease is a self-limiting condition caused by histiocyte proliferation within the sinusoids of lymph nodes and in extranodal tissue. It is a rare disease, particularly in children, that progresses with extensive lymphadenopathy. This paper reports on the case of a 2-year-old child with progressive cervical lymphadenopathy associated with persistent fever and radiological findings suggestive of lymphoma. Histopathological and immunohistochemistry studies of a lymph node biopsy established the diagnosis of Rosai-Dorfman disease. Both lymphadenopathy and fever resolved spontaneously. Associação Brasileira de Hematologia e Hemoterapia 2011 /pmc/articles/PMC3415761/ /pubmed/23049324 http://dx.doi.org/10.5581/1516-8484.20110083 Text en http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Lima, Felipe Barbosa Barcelos, Pedro Samuel de Valões Constâncio, Ana Paula Nunes Nogueira, Cleto Dantas Melo-Filho, Antônio Aldo
spellingShingle	Lima, Felipe Barbosa Barcelos, Pedro Samuel de Valões Constâncio, Ana Paula Nunes Nogueira, Cleto Dantas Melo-Filho, Antônio Aldo Rosai-Dorfman disease with spontaneous resolution: case report of a child
author_facet	Lima, Felipe Barbosa Barcelos, Pedro Samuel de Valões Constâncio, Ana Paula Nunes Nogueira, Cleto Dantas Melo-Filho, Antônio Aldo
author_sort	Lima, Felipe Barbosa
title	Rosai-Dorfman disease with spontaneous resolution: case report of a child
title_short	Rosai-Dorfman disease with spontaneous resolution: case report of a child
title_full	Rosai-Dorfman disease with spontaneous resolution: case report of a child
title_fullStr	Rosai-Dorfman disease with spontaneous resolution: case report of a child
title_full_unstemmed	Rosai-Dorfman disease with spontaneous resolution: case report of a child
title_sort	rosai-dorfman disease with spontaneous resolution: case report of a child
description	Rosai-Dorfman disease is a self-limiting condition caused by histiocyte proliferation within the sinusoids of lymph nodes and in extranodal tissue. It is a rare disease, particularly in children, that progresses with extensive lymphadenopathy. This paper reports on the case of a 2-year-old child with progressive cervical lymphadenopathy associated with persistent fever and radiological findings suggestive of lymphoma. Histopathological and immunohistochemistry studies of a lymph node biopsy established the diagnosis of Rosai-Dorfman disease. Both lymphadenopathy and fever resolved spontaneously.
publisher	Associação Brasileira de Hematologia e Hemoterapia
publishDate	2011
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415761/
_version_	1611548901207179264

Rosai-Dorfman disease with spontaneous resolution: case report of a child

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