Mutational Signatures of De-Differentiation in Functional Non-Coding Regions of Melanoma Genomes

Mutational Signatures of De-Differentiation in Functional Non-Coding Regions of Melanoma Genomes

Much emphasis has been placed on the identification, functional characterization, and therapeutic potential of somatic variants in tumor genomes. However, the majority of somatic variants lie outside coding regions and their role in cancer progression remains to be determined. In order to establish...

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Main Authors: Parker, Stephen C. J., Gartner, Jared, Cardenas-Navia, Isabel, Wei, Xiaomu, Ozel Abaan, Hatice, Ajay, Subramanian S., Hansen, Nancy F., Song, Lingyun, Bhanot, Umesh K., Killian, J. Keith, Gindin, Yevgeniy, Walker, Robert L., Meltzer, Paul S., Mullikin, James C., Furey, Terrence S., Crawford, Gregory E., Rosenberg, Steven A., Samuels, Yardena, Margulies, Elliott H.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415438/

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