5-Formyl- and 5-carboxyl-cytosine reduce the rate and substrate specificity of RNA polymerase II transcription
While the roles of 5-methyl-cytosine and 5-hydroxymethyl-cytosine in epigenetic regulation of gene expression are well-established, the functional effects of 5-formyl-cytosine and 5-carboxyl-cytosine in the genome on transcription are not clear. Here we report the first systematic study of the effec...
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Bibliographic Details
Main Authors: |
Kellinger, Matthew W.,
Song, Chun-Xiao,
Chong, Jenny,
Lu, Xing-Yu,
He, Chuan,
Wang, Dong |
Format: | Online
|
Language: | English |
Published: |
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414690/
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