Protection from Inflammatory Organ Damage in a Murine Model of Hemophagocytic Lymphohistiocytosis Using Treatment with IL-18 Binding Protein

Protection from Inflammatory Organ Damage in a Murine Model of Hemophagocytic Lymphohistiocytosis Using Treatment with IL-18 Binding Protein

Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening condition due to the association of an infectious agent with lymphocyte cytotoxicity defects, either of congenital genetic origin in children or presumably acquired in adults. In HLH patients, an excess of lymphocyte or macrophage cytoki...

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Bibliographic Details
Main Authors: Chiossone, Laura, Audonnet, Sandra, Chetaille, Bruno, Chasson, Lionel, Farnarier, Catherine, Berda-Haddad, Yael, Jordan, Stefan, Koszinowski, Ulrich H., Dalod, Marc, Mazodier, Karin, Novick, Daniela, Dinarello, Charles A., Vivier, Eric, Kaplanski, Gilles
Format: Online
Language:English
Published: Frontiers Research Foundation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413989/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413989/

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