Transgenerational Effects of Prenatal Synthetic Glucocorticoids on Hypothalamic-Pituitary-Adrenal Function

Approximately 10% of pregnant women are at risk of preterm delivery and receive synthetic glucocorticoids (sGC) to promote fetal lung development. Studies have indicated that prenatal sGC therapy modifies hypothalamic-pituitary-adrenal (HPA) function in first-generation (F1) offspring. The objective...

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Bibliographic Details
Main Authors: Iqbal, Majid, Moisiadis, Vasilis G., Kostaki, Alisa, Matthews, Stephen G.
Format: Online
Language:English
Published: Endocrine Society 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413075/