Crystal Structures of Human Pyridoxal Kinase in Complex with the Neurotoxins, Ginkgotoxin and Theophylline: Insights into Pyridoxal Kinase Inhibition

Crystal Structures of Human Pyridoxal Kinase in Complex with the Neurotoxins, Ginkgotoxin and Theophylline: Insights into Pyridoxal Kinase Inhibition

Several drugs and natural compounds are known to be highly neurotoxic, triggering epileptic convulsions or seizures, and causing headaches, agitations, as well as other neuronal symptoms. The neurotoxic effects of some of these compounds, including theophylline and ginkgotoxin, have been traced to t...

Full description

Bibliographic Details
Main Authors: Gandhi, Amit K., Desai, Jigar V., Ghatge, Mohini S., di Salvo, Martino L., Di Biase, Stefano, Danso-Danquah, Richmond, Musayev, Faik N., Contestabile, Roberto, Schirch, Verne, Safo, Martin K.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412620/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412620/

Similar Items