Proteomic Profiling of a Mouse Model for Ovarian Granulosa Cell Tumor Identifies VCP as a Highly Sensitive Serum Tumor Marker in Several Human Cancers

Proteomic Profiling of a Mouse Model for Ovarian Granulosa Cell Tumor Identifies VCP as a Highly Sensitive Serum Tumor Marker in Several Human Cancers

The initial aim of this study was to identify novel serum diagnostic markers for the human ovarian granulosa cell tumor (GCT), a tumor that represents up to 5% of all ovarian cancers. To circumvent the paucity of human tissues available for analyses, we used the Ctnnb1 tm1Mmt/+;Pten tm1Hwu/tmiHwu;Am...

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Bibliographic Details
Main Authors: Laguë, Marie-Noëlle, Romieu-Mourez, Raphaëlle, Bonneil, Éric, Boyer, Alexandre, Pouletty, Nicolas, Mes-Masson, Anne-Marie, Thibault, Pierre, Nadeau, Marie-Ève, Boerboom, Derek
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411637/

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