Approaches to enhancing the retroviral transduction of human synoviocytes

This report concerns a clinical trial for rheumatoid arthritis (RA), approved by the US National Institutes of Health and the Food and Drug Administration. An amphotropic retrovirus (MFG-IRAP) was used ex vivo to transfer a cDNA encoding human interleukin-1 receptor antagonist (IL-1Ra) to synovium....

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Bibliographic Details
Main Authors: Del Vecchio, Maria A, Georgescu, Helga I, McCormack, James E, Robbins, Paul D, Evans, Christopher H
Format: Online
Language:English
Published: BioMed Central 2001
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC34116/