Analysis of Cyclin D1 in Breast Cancer: A Call to Arms

The oncogenic capabilities of the cell cycle protein cyclin D1 have long been established in a breast cancer setting. The CCND1 gene is amplified in up to 15 % of breast tumors, with overexpression of its corresponding protein found in up to 50 % of cases. While gene amplification is consistently as...

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Bibliographic Details
Main Authors: Tobin, Nicholas P., Bergh, Jonas
Format: Online
Language:English
Published: Current Science Inc. 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410026/