A Role for Toll-Like Receptor Mediated Signals in Neutrophils in the Pathogenesis of the Anti-Phospholipid Syndrome

The anti-phospholipid syndrome (APS) is characterized by recurrent thrombosis and occurrence of anti-phospholipid antibodies (aPL). aPL are necessary, but not sufficient for the clinical manifestations of APS. Growing evidence suggests a role of innate immune cells, in particular polymorphonuclear n...

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Bibliographic Details
Main Authors: Gladigau, Gerd, Haselmayer, Philipp, Scharrer, Inge, Munder, Markus, Prinz, Nadine, Lackner, Karl, Schild, Hansjörg, Stein, Pamela, Radsak, Markus P.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409186/