Effect of Tumour Necrosis Factor-Alpha on Estrogen Metabolic Pathways in Breast Cancer Cells

Tumor necrosis factor-alpha (TNF-α) is a proinflammatory cytokine that has been linked to breast cancer development. Estrogen metabolic pathway is also involved in breast carcinogenesis and DNA adducts formation. In this study we investigated the effect of TNF-α on the estrogen metabolic pathway in...

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Bibliographic Details
Main Authors: Kamel, Marwa, Shouman, Samia, El-Merzebany, Mahmoud, Kilic, Gokhan, Veenstra, Timothy, Saeed, Muhammad, Wagih, Mohamed, Diaz-Arrastia, Concepcion, Patel, Deepa, Salama, Salama
Format: Online
Language:English
Published: Ivyspring International Publisher 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408695/