Comparison of Gene Expression Profiling in Sarcomas and Mesenchymal Stem Cells Identifies Tumorigenic Pathways in Chemically Induced Rat Sarcoma Model

Mesenchymal stem cells (MSCs) are believed to be the cell of origin for most sarcomas including osteosarcoma and malignant fibrous histiocytoma (MFH/UPS). To identify the signaling pathways involved in sarcoma pathogenesis, we compared gene expression profiles in rat osteosarcoma and MFH cells with...

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Bibliographic Details
Main Authors: Honoki, Kanya, Fujii, Hiromasa, Tohma, Yasuaki, Tsujiuchi, Toshifumi, Kido, Akira, Tsukamoto, Shinji, Mori, Toshio, Tanaka, Yasuhito
Format: Online
Language:English
Published: International Scholarly Research Network 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407640/