Myelopoiesis and Myeloid Leukaemogenesis in the Zebrafish

Over the past ten years, studies using the zebrafish model have contributed to our understanding of vertebrate haematopoiesis, myelopoiesis, and myeloid leukaemogenesis. Novel insights into the conservation of haematopoietic lineages and improvements in our capacity to identify, isolate, and culture...

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Main Authors:	Forrester, A. Michael, Berman, Jason N., Payne, Elspeth M.
Format:	Online
Language:	English
Published:	Hindawi Publishing Corporation 2012
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407620/

id	pubmed-3407620
recordtype	oai_dc
spelling	pubmed-34076202012-07-31 Myelopoiesis and Myeloid Leukaemogenesis in the Zebrafish Forrester, A. Michael Berman, Jason N. Payne, Elspeth M. Review Article Over the past ten years, studies using the zebrafish model have contributed to our understanding of vertebrate haematopoiesis, myelopoiesis, and myeloid leukaemogenesis. Novel insights into the conservation of haematopoietic lineages and improvements in our capacity to identify, isolate, and culture such haematopoietic cells continue to enhance our ability to use this simple organism to address disease biology. Coupled with the strengths of the zebrafish embryo to dissect developmental myelopoiesis and the continually expanding repertoire of models of myeloid malignancies, this versatile organism has established its niche as a valuable tool to address key questions in the field of myelopoiesis and myeloid leukaemogenesis. In this paper, we address the recent advances and future directions in the field of myelopoiesis and leukaemogenesis using the zebrafish system. Hindawi Publishing Corporation 2012 2012-07-19 /pmc/articles/PMC3407620/ /pubmed/22851971 http://dx.doi.org/10.1155/2012/358518 Text en Copyright © 2012 A. Michael Forrester et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Forrester, A. Michael Berman, Jason N. Payne, Elspeth M.
spellingShingle	Forrester, A. Michael Berman, Jason N. Payne, Elspeth M. Myelopoiesis and Myeloid Leukaemogenesis in the Zebrafish
author_facet	Forrester, A. Michael Berman, Jason N. Payne, Elspeth M.
author_sort	Forrester, A. Michael
title	Myelopoiesis and Myeloid Leukaemogenesis in the Zebrafish
title_short	Myelopoiesis and Myeloid Leukaemogenesis in the Zebrafish
title_full	Myelopoiesis and Myeloid Leukaemogenesis in the Zebrafish
title_fullStr	Myelopoiesis and Myeloid Leukaemogenesis in the Zebrafish
title_full_unstemmed	Myelopoiesis and Myeloid Leukaemogenesis in the Zebrafish
title_sort	myelopoiesis and myeloid leukaemogenesis in the zebrafish
description	Over the past ten years, studies using the zebrafish model have contributed to our understanding of vertebrate haematopoiesis, myelopoiesis, and myeloid leukaemogenesis. Novel insights into the conservation of haematopoietic lineages and improvements in our capacity to identify, isolate, and culture such haematopoietic cells continue to enhance our ability to use this simple organism to address disease biology. Coupled with the strengths of the zebrafish embryo to dissect developmental myelopoiesis and the continually expanding repertoire of models of myeloid malignancies, this versatile organism has established its niche as a valuable tool to address key questions in the field of myelopoiesis and myeloid leukaemogenesis. In this paper, we address the recent advances and future directions in the field of myelopoiesis and leukaemogenesis using the zebrafish system.
publisher	Hindawi Publishing Corporation
publishDate	2012
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407620/
_version_	1611546272091602944

Myelopoiesis and Myeloid Leukaemogenesis in the Zebrafish

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