Promoter Strength Driving TetR Determines the Regulatory Properties of Tet-Controlled Expression Systems

Bacteria frequently rely on transcription repressors and activators to alter gene expression patterns in response to changes in the surrounding environment. Tet repressor (TetR) is a paradigm transcription factor that senses the environmental state by binding small molecule effectors, the tetracycli...

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Bibliographic Details
Main Authors: Georgi, Christiane, Buerger, Julia, Hillen, Wolfgang, Berens, Christian
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407185/