Skeletal muscle damage and impaired regeneration due to LPL-mediated lipotoxicity
According to the concept of lipotoxicity, ectopic accumulation of lipids in non-adipose tissue induces pathological changes. The most prominent effects are seen in fatty liver disease, lipid cardiomyopathy, non-insulin-dependent diabetes mellitus, insulin resistance and skeletal muscle myopathy. We...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406590/ |