Influence of point mutations on the stability, dimerization, and oligomerization of human cystatin C and its L68Q variant
Human cystatin C (hCC) is a small but very intriguing protein. Produced by all nucleated cells is found in almost all tissues and body fluids where, at physiological conditions, plays a role of a very potent inhibitor of cysteine proteases. Biologically active hCC is a monomeric protein but during c...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Frontiers Media S.A.
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406405/ |