Let-7b/c Enhance the Stability of a Tissue-Specific mRNA during Mammalian Organogenesis as Part of a Feedback Loop Involving KSRP

Let-7b/c Enhance the Stability of a Tissue-Specific mRNA during Mammalian Organogenesis as Part of a Feedback Loop Involving KSRP

Gene silencing mediated by either microRNAs (miRNAs) or Adenylate/uridylate-rich elements Mediated mRNA Degradation (AMD) is a powerful way to post-transcriptionally modulate gene expression. We and others have reported that the RNA–binding protein KSRP favors the biogenesis of select miRNAs (includ...

Full description

Bibliographic Details
Main Authors: Repetto, Emanuela, Briata, Paola, Kuziner, Nathalie, Harfe, Brian D., McManus, Michael T., Gherzi, Roberto, Rosenfeld, Michael G., Trabucchi, Michele
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405994/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405994/

Similar Items