Digital clocks: simple Boolean models can quantitatively describe circadian systems

The gene networks that comprise the circadian clock modulate biological function across a range of scales, from gene expression to performance and adaptive behaviour. The clock functions by generating endogenous rhythms that can be entrained to the external 24-h day–night cycle, enabling organisms t...

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Bibliographic Details
Main Authors: Akman, Ozgur E., Watterson, Steven, Parton, Andrew, Binns, Nigel, Millar, Andrew J., Ghazal, Peter
Format: Online
Language:English
Published: The Royal Society 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405750/