Effect of Adjuvants on Responses to Skin Immunization by Microneedles Coated with Influenza Subunit Vaccine

Recent studies have demonstrated the effectiveness of vaccine delivery to the skin by vaccine-coated microneedles; however there is little information on the effects of adjuvants using this approach for vaccination. Here we investigate the use of TLR ligands as adjuvants with skin-based delivery of...

Full description

Bibliographic Details
Main Authors: Weldon, William C., Zarnitsyn, Vladimir G., Esser, E. Stein, Taherbhai, Misha T., Koutsonanos, Dimitrios G., Vassilieva, Elena V., Skountzou, Ioanna, Prausnitz, Mark R., Compans, Richard W.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405087/