Silibinin Inhibits HIV-1 Infection by Reducing Cellular Activation and Proliferation

Silibinin Inhibits HIV-1 Infection by Reducing Cellular Activation and Proliferation

Purified silymarin-derived natural products from the milk thistle plant (Silybum marianum) block hepatitis C virus (HCV) infection and inhibit T cell proliferation in vitro. An intravenous formulation of silibinin (SIL), a major component of silymarin, displays anti-HCV effects in humans and also in...

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Bibliographic Details
Main Authors: McClure, Janela, Lovelace, Erica S., Elahi, Shokrollah, Maurice, Nicholas J., Wagoner, Jessica, Dragavon, Joan, Mittler, John E., Kraft, Zane, Stamatatos, Leonidis, Horton, Helen, De Rosa, Stephen C., Coombs, Robert W., Polyak, Stephen J.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404953/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404953/

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