Application of iTRAQ Reagents to Relatively Quantify the Reversible Redox State of Cysteine Residues

Cysteines are one of the most rarely used amino acids, but when conserved in proteins they often play critical roles in structure, function, or regulation. Reversible cysteine modifications allow for potential redox regulation of proteins. Traditional measurement of the relative absolute quantity of...

Full description

Bibliographic Details
Main Authors: McDonagh, Brian, Martínez-Acedo, Pablo, Vázquez, Jesús, Padilla, C. Alicia, Sheehan, David, Bárcena, José Antonio
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403169/