A Novel Viral SOCS from Infectious Spleen and Kidney Necrosis Virus: Interacts with Jak1 and Inhibits IFN-α Induced Stat1/3 Activation

Interferon (IFN)-induced Janus kinase (Jak)/signal transducer and activator of transcription (Stat) pathway is important in controlling immune responses and is negatively response-regulated by the suppressor of cytokine signaling (SOCS) proteins. However, several viruses have developed various strat...

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Bibliographic Details
Main Authors: Guo, Chang-Jun, Yang, Li-Shi, Zhang, Ying-Fen, Wu, Yan-Yan, Weng, Shao-Ping, Yu, Xiao-Qiang, He, Jian-Guo
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402483/