A Novel Viral SOCS from Infectious Spleen and Kidney Necrosis Virus: Interacts with Jak1 and Inhibits IFN-α Induced Stat1/3 Activation
Interferon (IFN)-induced Janus kinase (Jak)/signal transducer and activator of transcription (Stat) pathway is important in controlling immune responses and is negatively response-regulated by the suppressor of cytokine signaling (SOCS) proteins. However, several viruses have developed various strat...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402483/ |