Genome-wide profiles of H2AX and γ-H2AX differentiate endogenous and exogenous DNA damage hotspots in human cells

Genome-wide profiles of H2AX and γ-H2AX differentiate endogenous and exogenous DNA damage hotspots in human cells

Phosphorylation of the histone variant H2AX forms γ-H2AX that marks DNA double-strand break (DSB). Here, we generated the sequencing-based maps of H2AX and γ-H2AX positioning in resting and proliferating cells before and after ionizing irradiation. Genome-wide locations of possible endogenous and ex...

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Bibliographic Details
Main Authors: Seo, Jungmin, Kim, Sang Cheol, Lee, Heun-Sik, Kim, Jung Kyu, Shon, Hye Jin, Salleh, Nur Lina Mohd, Desai, Kartiki Vasant, Lee, Jae Ho, Kang, Eun-Suk, Kim, Jin Sung, Choi, Jung Kyoon
Format: Online
Language:English
Published: Oxford University Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401470/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401470/

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