Mechanism of strand displacement synthesis by DNA replicative polymerases

Mechanism of strand displacement synthesis by DNA replicative polymerases

Replicative holoenzymes exhibit rapid and processive primer extension DNA synthesis, but inefficient strand displacement DNA synthesis. We investigated the bacteriophage T4 and T7 holoenzymes primer extension activity and strand displacement activity on a DNA hairpin substrate manipulated by a magne...

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Bibliographic Details
Main Authors: Manosas, Maria, Spiering, Michelle M., Ding, Fangyuan, Bensimon, David, Allemand, Jean-François, Benkovic, Stephen J., Croquette, Vincent
Format: Online
Language:English
Published: Oxford University Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401438/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401438/

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