Critical amino acids in Escherichia coli UmuC responsible for sugar discrimination and base-substitution fidelity

Critical amino acids in Escherichia coli UmuC responsible for sugar discrimination and base-substitution fidelity

The active form of Escherichia coli DNA polymerase V responsible for damage-induced mutagenesis is a multiprotein complex (UmuD′2C-RecA-ATP), called pol V Mut. Optimal activity of pol V Mut in vitro is observed on an SSB-coated single-stranded circular DNA template in the presence of the β/γ complex...

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Bibliographic Details
Main Authors: Vaisman, Alexandra, Kuban, Wojciech, McDonald, John P., Karata, Kiyonobu, Yang, Wei, Goodman, Myron F., Woodgate, Roger
Format: Online
Language:English
Published: Oxford University Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401427/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401427/

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