The Epithelial-Mesenchymal Transition (EMT) Regulatory Factor SLUG (SNAI2) Is a Downstream Target of SPARC and AKT in Promoting Melanoma Cell Invasion

The Epithelial-Mesenchymal Transition (EMT) Regulatory Factor SLUG (SNAI2) Is a Downstream Target of SPARC and AKT in Promoting Melanoma Cell Invasion

During progression of melanoma, malignant melanocytes can be reprogrammed into mesenchymal-like cells through a process similar to epithelial-mesenchymal transition (EMT), which is associated with downregulation of the junctional protein E-cadherin and acquisition of a migratory phenotype. Recent ev...

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Bibliographic Details
Main Authors: Fenouille, Nina, Tichet, Mélanie, Dufies, Maeva, Pottier, Anaïs, Mogha, Ariane, Soo, Julia K., Rocchi, Stéphane, Mallavialle, Aude, Galibert, Marie-Dominique, Khammari, Amir, Lacour, Jean-Philippe, Ballotti, Robert, Deckert, Marcel, Tartare-Deckert, Sophie
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401237/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401237/

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