Cleavage of Phage DNA by the Streptococcus thermophilus CRISPR3-Cas System

Streptococcus thermophilus, similar to other Bacteria and Archaea, has developed defense mechanisms to protect cells against invasion by foreign nucleic acids, such as virus infections and plasmid transformations. One defense system recently described in these organisms is the CRISPR-Cas system (Cl...

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Bibliographic Details
Main Authors: Magadán, Alfonso H., Dupuis, Marie-Ève, Villion, Manuela, Moineau, Sylvain
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401199/