Metastatic melanoma and vemurafenib: novel approaches

Metastatic melanoma (MM) presents a treatment challenge to oncologists worldwide. Dacarbazine is the first line chemotherapy treatment for MM, though the overall response rates are very poor. Recently, the v-raf murine sarcoma viral oncogene homolog B1 (BRAF) V600 mutation was found to play a main r...

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Bibliographic Details
Main Author: De Mello, Ramon Andrade
Format: Online
Language:English
Published: PAGEPress Publications 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401159/