Differential Impact of the HEN1 Homolog HENN-1 on 21U and 26G RNAs in the Germline of Caenorhabditis elegans

RNA interference (RNAi)–related pathways affect gene activity by sequence-specific recruitment of Ago proteins to mRNA target molecules. The sequence specificity of this process stems from small RNA (sRNA) co-factors bound by the Ago protein. Stability of sRNA molecules in some pathways is in part r...

Full description

Bibliographic Details
Main Authors: Kamminga, Leonie M., van Wolfswinkel, Josien C., Luteijn, Maartje J., Kaaij, Lucas J. T., Bagijn, Marloes P., Sapetschnig, Alexandra, Miska, Eric A., Berezikov, Eugene, Ketting, René F.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400576/