Development of an All-in-One Inducible Lentiviral Vector for Gene Specific Analysis of Reprogramming

Fair comparison of reprogramming efficiencies and in vitro differentiation capabilities among induced pluripotent stem cell (iPSC) lines has been hampered by the cellular and genetic heterogeneity of de novo infected somatic cells. In order to address this problem, we constructed a single cassette a...

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Bibliographic Details
Main Authors: Yamaguchi, Tomoyuki, Hamanaka, Sanae, Kamiya, Akihide, Okabe, Motohito, Kawarai, Mami, Wakiyama, Yukiko, Umino, Ayumi, Hayama, Tomonari, Sato, Hideyuki, Lee, Youn-Su, Kato-Itoh, Megumi, Masaki, Hideki, Kobayashi, Toshihiro, Yamazaki, Satoshi, Nakauchi, Hiromitsu
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399796/