18α-Glycyrrhetinic Acid Down-Regulates Expression of Type I and III Collagen via TGF-Β1/Smad Signaling Pathway in Human and Rat Hepatic Stellate Cells

18α-Glycyrrhetinic Acid Down-Regulates Expression of Type I and III Collagen via TGF-Β1/Smad Signaling Pathway in Human and Rat Hepatic Stellate Cells

Objective: To investigate the effects of 18α-glycyrrhetinic acid (18α-GA) on the expression of type I and III collagen in human and rat hepatic stellate cells (HSC) and to explore the role of TGF-β1/Smad signaling pathway involved.

Bibliographic Details
Main Authors: Zong, Lei, Qu, Ying, Xu, Ming-yi, Dong, Yu-wei, Lu, Lun-gen
Format: Online
Language:English
Published: Ivyspring International Publisher 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399217/
id pubmed-3399217
recordtype oai_dc
spelling pubmed-33992172012-07-18 18α-Glycyrrhetinic Acid Down-Regulates Expression of Type I and III Collagen via TGF-Β1/Smad Signaling Pathway in Human and Rat Hepatic Stellate Cells Zong, Lei Qu, Ying Xu, Ming-yi Dong, Yu-wei Lu, Lun-gen Research Paper Objective: To investigate the effects of 18α-glycyrrhetinic acid (18α-GA) on the expression of type I and III collagen in human and rat hepatic stellate cells (HSC) and to explore the role of TGF-β1/Smad signaling pathway involved. Ivyspring International Publisher 2012-07-10 /pmc/articles/PMC3399217/ /pubmed/22811611 http://dx.doi.org/10.7150/ijms.4395 Text en © Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Zong, Lei
Qu, Ying
Xu, Ming-yi
Dong, Yu-wei
Lu, Lun-gen
spellingShingle Zong, Lei
Qu, Ying
Xu, Ming-yi
Dong, Yu-wei
Lu, Lun-gen
18α-Glycyrrhetinic Acid Down-Regulates Expression of Type I and III Collagen via TGF-Β1/Smad Signaling Pathway in Human and Rat Hepatic Stellate Cells
author_facet Zong, Lei
Qu, Ying
Xu, Ming-yi
Dong, Yu-wei
Lu, Lun-gen
author_sort Zong, Lei
title 18α-Glycyrrhetinic Acid Down-Regulates Expression of Type I and III Collagen via TGF-Β1/Smad Signaling Pathway in Human and Rat Hepatic Stellate Cells
title_short 18α-Glycyrrhetinic Acid Down-Regulates Expression of Type I and III Collagen via TGF-Β1/Smad Signaling Pathway in Human and Rat Hepatic Stellate Cells
title_full 18α-Glycyrrhetinic Acid Down-Regulates Expression of Type I and III Collagen via TGF-Β1/Smad Signaling Pathway in Human and Rat Hepatic Stellate Cells
title_fullStr 18α-Glycyrrhetinic Acid Down-Regulates Expression of Type I and III Collagen via TGF-Β1/Smad Signaling Pathway in Human and Rat Hepatic Stellate Cells
title_full_unstemmed 18α-Glycyrrhetinic Acid Down-Regulates Expression of Type I and III Collagen via TGF-Β1/Smad Signaling Pathway in Human and Rat Hepatic Stellate Cells
title_sort 18α-glycyrrhetinic acid down-regulates expression of type i and iii collagen via tgf-β1/smad signaling pathway in human and rat hepatic stellate cells
description Objective: To investigate the effects of 18α-glycyrrhetinic acid (18α-GA) on the expression of type I and III collagen in human and rat hepatic stellate cells (HSC) and to explore the role of TGF-β1/Smad signaling pathway involved.
publisher Ivyspring International Publisher
publishDate 2012
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399217/
_version_ 1611543736946262016

Similar Items