Model-driven multi-omic data analysis elucidates metabolic immunomodulators of macrophage activation

Genome-scale metabolic network reconstruction and analysis of the murine leukemic macrophage cell line RAW 264.7 reveal a complementary relationship between how known metabolic immunomodulators are biochemically processed and their role in macrophage activation.

Bibliographic Details
Main Authors: Bordbar, Aarash, Mo, Monica L, Nakayasu, Ernesto S, Schrimpe-Rutledge, Alexandra C, Kim, Young-Mo, Metz, Thomas O, Jones, Marcus B, Frank, Bryan C, Smith, Richard D, Peterson, Scott N, Hyduke, Daniel R, Adkins, Joshua N, Palsson, Bernhard O
Format: Online
Language:English
Published: Nature Publishing Group 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397418/