Optic Atrophy 1-Dependent Mitochondrial Remodeling Controls Steroidogenesis in Trophoblasts
During human pregnancy, placental trophoblasts differentiate and syncytialize into syncytiotrophoblasts that sustain progesterone production [1]. This process is accompanied by mitochondrial fragmentation and cristae remodeling [2], two facets of mitochondrial apoptosis, whose molecular mechanisms a...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Cell Press
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396839/ |