Acute Podocyte Vascular Endothelial Growth Factor (VEGF-A) Knockdown Disrupts alphaVbeta3 Integrin Signaling in the Glomerulus

Acute Podocyte Vascular Endothelial Growth Factor (VEGF-A) Knockdown Disrupts alphaVbeta3 Integrin Signaling in the Glomerulus

Podocyte or endothelial cell VEGF-A knockout causes thrombotic microangiopathy in adult mice. To study the mechanism involved in acute and local injury caused by low podocyte VEGF-A we developed an inducible, podocyte-specific VEGF-A knockdown mouse, and we generated an immortalized podocyte cell li...

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Bibliographic Details
Main Authors: Veron, Delma, Villegas, Guillermo, Aggarwal, Pardeep Kumar, Bertuccio, Claudia, Jimenez, Juan, Velazquez, Heino, Reidy, Kimberly, Abrahamson, Dale R., Moeckel, Gilbert, Kashgarian, Michael, Tufro, Alda
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396653/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396653/

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