Galectins as self/non-self recognition receptors in innate and adaptive immunity: an unresolved paradox

Galectins are characterized by their binding affinity for β-galactosides, a unique binding site sequence motif, and wide taxonomic distribution and structural conservation in vertebrates, invertebrates, protista, and fungi. Since their initial description, galectins were considered to bind endogenou...

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Bibliographic Details
Main Authors: Vasta, Gerardo R., Ahmed, Hafiz, Nita-Lazar, Mihai, Banerjee, Aditi, Pasek, Marta, Shridhar, Surekha, Guha, Prasun, Fernández-Robledo, José A.
Format: Online
Language:English
Published: Frontiers Research Foundation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396283/