Tat-Mediated p66shc Transduction Decreased Phosphorylation of Endothelial Nitric Oxide Synthase in Endothelial Cells

We evaluated the role of Tat-mediated p66shc transduction on the activation of endothelial nitric oxide synthase in cultured mouse endothelial cells. To construct the Tat-p66shc fusion protein, human full length p66shc cDNA was fused with the Tat-protein transduction domain. Transduction of TAT-p66s...

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Bibliographic Details
Main Authors: Lee, Sang Ki, Lee, Ji Young, Joo, Hee Kyoung, Cho, Eun Jung, Kim, Cuk Seong, Lee, Sang Do, Park, Jin Bong, Jeon, Byeong Hwa
Format: Online
Language:English
Published: The Korean Physiological Society and The Korean Society of Pharmacology 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394923/