SIFT web server: predicting effects of amino acid substitutions on proteins

The Sorting Intolerant from Tolerant (SIFT) algorithm predicts the effect of coding variants on protein function. It was first introduced in 2001, with a corresponding website that provides users with predictions on their variants. Since its release, SIFT has become one of the standard tools for cha...

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Bibliographic Details
Main Authors: Sim, Ngak-Leng, Kumar, Prateek, Hu, Jing, Henikoff, Steven, Schneider, Georg, Ng, Pauline C.
Format: Online
Language:English
Published: Oxford University Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394338/