A Toxoplasma gondii Pseudokinase Inhibits Host IRG Resistance Proteins

A secreted kinase from the parasitic protozoan, Toxoplasma gondii, is shown to cooperate with a phylogenetically related pseudokinase to phosphorylate and inactivate a mouse resistance protein of the IRG system.

Bibliographic Details
Main Authors: Fleckenstein, Martin C., Reese, Michael L., Könen-Waisman, Stephanie, Boothroyd, John C., Howard, Jonathan C., Steinfeldt, Tobias
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393671/