The Pathophysiology of Inhalational Brucellosis in Balb/c Mice

To characterize the clinical presentation and pathophysiology of inhalational brucellosis, Balb/c mice were challenged with Brucella melitensis 16M in a nose-only aerosol exposure chamber. A low dose of 1000 cfu/animal of B. melitensis resulted in 45% of mice with tissue burdens eight weeks post-cha...

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Bibliographic Details
Main Authors: Henning, Lisa N., Gillum, Karen T., Fisher, David A., Barnewall, Roy E., Krile, Robert T., Anderson, Michael S., Ryan, Michael J., Warren, Richard L.
Format: Online
Language:English
Published: Nature Publishing Group 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390596/