Toward an Integrative Computational Model of the Guinea Pig Cardiac Myocyte
The local control theory of excitation-contraction (EC) coupling asserts that regulation of calcium (Ca2+) release occurs at the nanodomain level, where openings of single L-type Ca2+ channels (LCCs) trigger openings of small clusters of ryanodine receptors (RyRs) co-localized within the dyad. A con...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Frontiers Research Foundation
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389778/ |