Chemo-enzymatic modification of poly-N-acetyllactosamine (LacNAc) oligomers and N,N-diacetyllactosamine (LacDiNAc) based on galactose oxidase treatment

The importance of glycans in biological systems is highlighted by their various functions in physiological and pathological processes. Many glycan epitopes on glycoproteins and glycolipids are based on N-acetyllactosamine units (LacNAc; Galβ1,4GlcNAc) and often present on extended poly-LacNAc glycan...

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Bibliographic Details
Main Authors: Kupper, Christiane E, Rosencrantz, Ruben R, Henßen, Birgit, Pelantová, Helena, Thönes, Stephan, Drozdová, Anna, Křen, Vladimir, Elling, Lothar
Format: Online
Language:English
Published: Beilstein-Institut 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388858/