Prenatal Excess Glucocorticoid Exposure and Adult Affective Disorders: A Role for Serotonergic and Catecholamine Pathways
Fetal glucocorticoid exposure is a key mechanism proposed to underlie prenatal ‘programming’ of adult affective behaviours such as depression and anxiety. Indeed, the glucocorticoid metabolising enzyme 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2), which is highly expressed in the placenta and...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
S. Karger AG
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388616/ |