High Resolution Discrimination of Clinical Mycobacterium tuberculosis Complex Strains Based on Single Nucleotide Polymorphisms

Recently, the diversity of the Mycobacterium tuberculosis complex (MTBC) population structure has been described in detail. Based on geographical separation and specific host pathogen co-evolution shaping MTBC virulence traits, at least 20 major lineages/genotypes have evolved finally leading to a c...

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Bibliographic Details
Main Authors: Homolka, Susanne, Projahn, Michaela, Feuerriegel, Silke, Ubben, Tanja, Diel, Roland, Nübel, Ulrich, Niemann, Stefan
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388094/