Mechanisms of long range silencing by imprinted macro non-coding RNAs

Non-coding (nc) RNA silencing of imprinted genes in extra-embryonic tissues provides a good model for understanding an underexamined aspect of gene regulation by macro or long ncRNAs, that is their action as long-range cis-silencers. Numerous long intergenic ncRNAs (lincRNAs) have been recently disc...

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Bibliographic Details
Main Authors: Pauler, Florian M, Barlow, Denise P, Hudson, Quanah J
Format: Online
Language:English
Published: Elsevier 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387373/