6-Shogaol Induces Apoptosis in Human Hepatocellular Carcinoma Cells and Exhibits Anti-Tumor Activity In Vivo through Endoplasmic Reticulum Stress

6-Shogaol is an active compound isolated from Ginger (Zingiber officinale Rosc). In this work, we demonstrated that 6-shogaol induces apoptosis in human hepatocellular carcinoma cells in relation to caspase activation and endoplasmic reticulum (ER) stress signaling. Proteomic analysis revealed that...

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Bibliographic Details
Main Authors: Hu, Rong, Zhou, Ping, Peng, Yong-Bo, Xu, Xiaojun, Ma, Jiang, Liu, Qun, Zhang, Lei, Wen, Xiao-Dong, Qi, Lian-Wen, Gao, Ning, Li, Ping
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387266/