Epstein-Barr Virus BGLF4 Kinase Retards Cellular S-Phase Progression and Induces Chromosomal Abnormality

Epstein-Barr virus (EBV) induces an uncoordinated S-phase-like cellular environment coupled with multiple prophase-like events in cells replicating the virus. The EBV encoded Ser/Thr kinase BGLF4 has been shown to induce premature chromosome condensation through activation of condensin and topoisome...

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Main Authors: Chang, Yu-Hsin, Lee, Chung-Pei, Su, Mei-Tzu, Wang, Jiin-Tarng, Chen, Jen-Yang, Lin, Su-Fang, Tsai, Ching-Hwa, Hsieh, Min-Jei, Takada, Kenzo, Chen, Mei-Ru
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387188/