The pathology of familial breast cancer: The pathology of familial breast cancer How do the functions of BRCA1 and BRCA2 relate to breast tumour pathology?
Women with mutations in the breast cancer susceptibility genes, BRCA1 and BRCA2, have an increased risk of developing breast cancer. Both BRCA1 and BRCA2 are thought to be tumour suppressor genes since the wild type alleles of these genes are lost in tumours from heterozygous carriers. Several funct...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
BioMed Central
1999
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386652/ |