Hypothermia-induced hyperphosphorylation: a new model to study tau kinase inhibitors

Hypothermia-induced hyperphosphorylation: a new model to study tau kinase inhibitors

Tau hyperphosphorylation is one hallmark of Alzheimer's disease (AD) pathology. Pharmaceutical companies have thus developed kinase inhibitors aiming to reduce tau hyperphosphorylation. One obstacle in screening for tau kinase inhibitors is the low phosphorylation levels of AD-related phospho-e...

Full description

Bibliographic Details
Main Authors: Bretteville, Alexis, Marcouiller, François, Julien, Carl, El Khoury, Noura B., Petry, Franck R., Poitras, Isabelle, Mouginot, Didier, Lévesque, Georges, Hébert, Sébastien S., Planel, Emmanuel
Format: Online
Language:English
Published: Nature Publishing Group 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386519/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386519/

Similar Items