Genome-wide Efficient Mixed Model Analysis for Association Studies

Linear mixed models have attracted considerable recent attention as a powerful and effective tool for accounting for population stratification and relatedness in genetic association tests. However, existing methods for exact computation of standard test statistics are computationally impractical for...

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Bibliographic Details
Main Authors: Zhou, Xiang, Stephens, Matthew
Format: Online
Language:English
Published: 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386377/