ICAM-1 Upregulation in Ethanol-Induced Fatty Murine Livers Promotes Injury and Sinusoidal Leukocyte Adherence after Transplantation
Background. Transplantation of ethanol-induced steatotic livers causes increased graft injury. We hypothesized that upregulation of hepatic ICAM-1 after ethanol produces increased leukocyte adherence, resulting in increased generation of reactive oxygen species (ROS) and injury after liver transpla...
Main Authors: | , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Hindawi Publishing Corporation
2012
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385666/ |